This paper critically evaluates an objection to introspective arguments for human freedom found within Spinoza's Ethics. The objection-- which we call Spinoza's dream argument -- challenges the evidentiary value of a person's experience of her own freedom by pointing out that some choices made within dreams are experienced as no less free than choices made while awake despite the fact that choices made within dreams are not free. After reconstructing Spinoza's dream argument, we critically evaluate it, concluding ultimately that it (...) fails in two respects. First, we draw upon the results of an experiment we conducted that suggests that dreamt choices are not experienced as free to the same extent as choices made while awake. Second, we argue that there is no compelling justification for the claim that choices made within dreams are not free. (shrink)

Introduction While quizzing during informed consent for research to ensure understanding has become commonplace, it is unclear whether the quizzing itself is problematic for potential participants. In this study, we address this issue in a multinational HIV prevention research trial enrolling injection drug users in China and Thailand. Methods Enrolment procedures included an informed consent comprehension quiz. An informed consent survey followed. Results 525 participants completed the informed consent survey (Heng County, China=255, Xinjiang, China=229, Chiang Mai, Thailand=41). Mean age was (...) 33 and mean educational level was 8 yrs. While quizzing was felt to be a good way to determine if a person understands the nature of clinical trial participation (97%) and participants did not generally find the quiz to be problematic, minorities of respondents felt pressured (6%); anxious (5%); bored (5%); minded (5%); and did not find the questions easy (13%). In multivariate analysis, lower educational level was associated with not minding the quizzing (6–10 yrs vs 0–5 yrs: OR=0.27, p=0.03; more than 11 yrs vs 0–5 yrs: OR=0.18, p=0.03). There were also site differences (Heng County vs Xinjiang) in feeling anxious (OR=0.07; p=<0.01), not minding (OR=0.26; p=0.03), being bored (OR=0.25; p=0.01) and not finding the questions easy (OR=0.10; p=<0.01). Conclusions Quizzing during the informed consent process can be problematic for a minority of participants. These problems may be associated with the setting in which research takes place and educational level. Further research is needed to develop, test and implement alternative methods of ensuring comprehension of informed consent. Trial Registration clinicaltrials.gov number NCT00270257. (shrink)

Field-Programmable Gate Arrays (FPGAs) have emerged as an attractive means of implementing logic circuits, providing instant manufacturing turnaround and negligible prototype costs. They hold the promise of replacing much of the VLSI market now held by mask-programmed gate arrays. FPGAs offer an affordable solution for customized VLSI, over a wide variety of applications, and have also opened up new possibilities in designing reconfigurable digital systems. Field-Programmable Gate Arrays discusses the most important aspects of FPGAs in a textbook manner. It provides (...) the reader with a focused view of the key issues, using a consistent notation and style of presentation. It provides detailed descriptions of commercially available FPGAs and an in-depth treatment of the FPGA architecture and CAD issues that are the subjects of current research. The material presented is of interest to a variety of readers, including those who are not familiar with FPGA technology, but wish to be introduced to it, as well as those who already have an understanding of FPGAs, but who are interested in learning about the research directions that are of current interest. (shrink)

Recent efforts in a range of scientific fields have emphasised research and methods concerning individual differences and individualisation. This article brings together various scientific disciplines—ecology, evolution, and animal behaviour; medicine and psychiatry; public health and sport/exercise science; sociology; psychology; economics and management science—and presents their research on individualisation. We then clarify the concept of individualisation as it appears in the disciplinary casework by distinguishing three kinds of individualisation studied in and across these disciplines: Individualisation ONE as creating/changing individual differences (the (...) process that generates differences between individuals: intrapopulation or intraspecific variation/heterogeneity); Individualisation TWO as individualising applications (the tailoring or customising of something—information, treatment, a product or service, etc.—for an individual or specific group of individuals); and Individualisation THREE as social changes influencing autonomy, risk, and responsibilities (the process discussed under the rubric of sociological individualisation theory). Moreover, we analyse conceptual links between individualisation and individuality, and characterise different sorts of individuality that the disciplines study. This paper aims to promote interdisciplinary research concerning individualisation by establishing a common conceptual-theoretical basis, while leaving room for disciplinary differences. (shrink)

It is no longer the fashion to imagine Herodotos a liar when he tells marvellous stories, for some of his most extraordinary statements have long since been shown to contain at least a substantial measure of truth. It is perhaps not sufficiently realized, however, that on occasion he misleads his readers and himself by too much critical unbelief in his materials and consequent application of the crude methods of mythological investigation then current. In other words, he often rationalizes in the (...) only way then possible, superficially altering the story so as to rid himself of the incredible details, or at all events, as I think, attributing to the actors motives which a somewhat drily rational mind could understand and approve or condemn. It is of course well known that at least the former method was a commonplace of the sophists, whose influence on Herodotos is manifest and widespread; it has been said, indeed, that it is much older than they and characteristically Ionic. L. Radermacher finds traces of it in the Odyssey itself and adds that, although we can sometimes catch the rationalizer at work, we cannot be sure of always doing so and ‘müssen annehmen, dass der Glaube an die Geschichtlichkeit ihrer Sage manche griechischen Autoren früh verführt hat, sie geschichtlicher zu erzählen als eigentlich erlaubt war’. This is a true and useful statement. Modern criticism has long learned to set aside ancient allegorizations of myths, about which I need say nothing, for the subject has been repeatedly and well handled by my colleague, Dr. J. Tate; it has often, however, confused ancient interpretation of myth with ancient criticism of saga. Euhemerism indeed is usually recognized for what it is, although even this is not always so; but uixere inepti ante Euhemerum multi, and their efforts are by no means always distinguished either from allegorizing or from real sagas. For an example of the former confusion I may refer to Stallbaum's note on Plato, Phaedrus, 29 C-D, where the reader is referred to the account given by Lobeck of the rise and growth of allegorization. But Plato says nothing at all of allegories in this passage. He quotes, with ironical admiration of its ‘wisdom’, a version of the story of Boreas and Oreithyia according to which she. was knocked off the Areiopagos, or some other place, by a strong north wind, and so was killed and consequently said to have been carried away by Boreas. He adds that it would be a laborious and dismal business to go through all the tales of wonder in that way, rationalizing the Hippocentaurs, Gorgons, Chimaira, Pegasos, and the rest out of existence; a wise saying which was uttered in vain for Palaiphatos and his kind. However, most moderns know a myth from a saga and an allegory from a crude rationalization which accepts the story as true except for the incredibilities and is quite ready to believe, for instance, in Romulus if we will but postulate that he was not snatched up to heaven but murdered and his body hidden. There is a much more subtle snare, consisting of a story which, although rationalized, is well told, and Herodotos in this respect can be a notable offender, for he never tells a story ill. (shrink)

In this paper, we examine how organizations’ impression management evolves in response to rising stakeholder pressures regarding organizations’ corporate responsibility initiatives. We conducted a comparative case study analysis over a period of 13 years for two organizations—Exxon and BP—that took extreme initial stances on climate change. We found that as stakeholder pressures rose, their IM tactics unfolded in four phases: advocating the initial stance, sensegiving to clarify the initial stance, image repairing, and adjusting the stance. Taken together, our analysis (...) of IM over these four phases provides three key insights about the evolution of IM in the face of rising pressures. First, when faced with stakeholder pressures, it seems that organizations do not immediately resort to conforming but tend to give in gradually when pressures increase and start to come from relatively powerful stakeholders. Second, evolution of IM seems to be characterized by path dependence, i.e., even as organizations’ positions evolve, they continue to show their conviction in their initial positions and try to convey that their subsequent positions flow logically from the previous ones. Finally, IM involves navigation between symbolism and substance, and companies tend to strive toward harmonizing their symbolic and substantive actions as stakeholder pressure increases. (shrink)

Professor D'Arcy W. Thompson has recently revived a conjecture of Lauth on Geoponica, XIII, 8, 1, which runs as follows: εις οκ σονται ν χωρ ν νθιονἢ ρτεμσιον ἢ βρτονον περ τν πα$$υλιν υτεσς. τος δ ντας λσεις ν . The conjecture is that ντας is the Egyptian hontasu, ‘lizard.’ That this would make sense is obvious; but the usage of the Geop. itself, to say nothing of other authors, indicates that the word is simply what it appears to be, (...) namely the pres. part, of εμ. Thus we find in X, 46 τ ςκα σκληκας ¿ π¿ισειν μλλων φυτεειν μπξς σκλλ τν κλδ¿ν, τ¿ς δ ντας ναιρες ν κ.τ.λ. Here the explanation ‘lizards’ would hardly be reasonable; still more cogent, however, is XII, 8, 2–3, ¿κ σονται … τς δ οσας κμπας διαθερς, where no such conjecture is possible. Not dissimilar is XII, 19, 9, τς τε γρ οσας ψλλας θερεικα λλας οκ γενσθαι. All these extracts are taken from authors of the second and third centuries A.D., though we have no means of knowing how closely their actual wording is followed; it is therefore in point to cite a passage of Galen, the opening paragraph of the tractate περ αρσεων Medicine, he says, has for its aim health, and a physician must know how to bring about health if absent and preserve it if present . καλεται δ, he continues, τ μν ργαζμενα τν μ οσαν γειατν τε καβοηθματα, τ δ φυλττοντα τν οσαν γιειν διαιτματα. In other words, ὢν can be used in much the same sense as παρν. This is no novelty of Roman times, for we may compare, for instance, Soph. Ant. 1109, ο ' ντες ο τ'πντες, and El, 305 τς οσας … κα τς ποσας λπδας. (shrink)

γχΣεμλη ӣτως καλετо, says the lexicographer, from a source which is unknown, but would appear to be late, since it uses a past tense. Where or by whom Semele was so named is not stated, nor has any explanation been given, so far as I know, that is at all satisfactory, for she certainly has nothing to do with swords. I suggest that she was never called anything of the kind, and the statement arises from a comedian's jest. Aristophanes speaks (...) of Διννσоς Σιαμνоν, and the scholiast is careful to inform the humourless who read this play that it is a joke, παρ' πνоιαν, instead of νς Δις. So no lexicographer ever tells us that Stamnios is a title of Zeus. I suggest that somewhere, by Aristophanes or another, Dionysos was called νς γχоς, ‘son of Pour-Out,’ a comic formation from γχεν. If such a passage came into the late classical or the mediaeval world unguarded by a scholiast, it would be taken with the same seriousness which has attended sundry witticisms directed at Kleon and other butts of Comedy. The reasoning would be most syllogistic and accurate, as thus: Encho is the mother of Dionysos. But Semele is the mother of Dionysos. Therefore Encho is Semele, Q.E.D. (shrink)

Alzheimer's disease is characterized by plaques of amyloid-beta peptide, cleaved from amyloid-beta protein precursor . Our hypothesis is that lifespan profiles of AD-associated mRNA and protein levels in monkeys would differ from mice and that differential lifespan expression profiles would be useful to understand human AD pathogenesis. We compared profiles of AbetaPP mRNA, AbetaPP protein, and Abeta levels in rodents and primates. We also tracked a transcriptional regulator of the AbetaPP gene, specificity protein 1 , and the beta amyloid precursor (...) cleaving enzyme . In mice, AbetaPP and SP1 mRNA and their protein products were elevated late in life; Abeta levels declined in old age. In monkeys, SP1, AbetaPP, and BACE1 mRNA declined in old age, while protein products and Abeta levels rose. Proteolytic processing in both species did not match production of Abeta. In primates, AbetaPP and SP1 mRNA levels coordinate, but an inverse relationship exists with corresponding protein products as well as Abeta levels. Comparison of human DNA and mRNA sequences to monkey and mouse counterparts revealed structural features that may explain differences in transcriptional and translational processing. These findings are important for selecting appropriate models for AD and other age-related diseases. (shrink)

One third of the transcendental dialectic in Kant's Critique of Pure Reason is devoted to demolishing the pseudo-science of rational psychology. In this part of his work Kant attacks the idea that there is an ultimate subject of experience — the ‘I’ or Self — which can only be investigated and understood intellectually. The belief that such a study is possible is natural to human reason; but it is based on demonstrable error. Kant tries to exorcize our minds from falling (...) prey to this mistake. (shrink)

"Qui domine la littérature mondiale?" demandait Strindberg. "Péladan, Gorki, Maeterlink, Kipling" répondait-il. De ces noms, seul celui de Péladan n'évoque plus un livre précis pour nos contemporains. Certains se souviennent d'un auteur de la fin du siècle dernier qui s'était rendu célèbre par ses extravagances vestimentaires : son pourpoint Renaissance et sa barbe à l'assyrienne dans le Paris de la Belle Epoque défrayait la chronique. Les journalistes ont aussi consacré une large place à ses démêlés avec d'autres occultistes. Ses salons (...) de la Rose-Croix, pour lesquels Satie composa des sonneries, eurent une grande renommée et sont importants pour qui s'intéresse à l'histoire de l'art. Péladan, avec un sens certain de la publicité, s'était proclamé S.A.R., titre assyrien qui en faisait un descendant mythique des Mages chaldéens. C'est ce titre qui a assuré sa notoriété jusqu'à nos jours. D'androgynes pervers en femmes violées, mêlant la magie aux thèmes décadents, ses romans présentent un tableau étonnant de la pensée fin de siècle. Ce texte veut démontrer que Joséphin Péladan, qui eut des admirateurs comme Jarry ou Paul Valéry, n'était pas qu'un dandy excentrique, un farfelu 1900 teinté d'ésotérisme mais un authentique écrivain. Il existe un récit de Borgès qui raconte l'histoire d'un peintre qui voulut faire un tableau de l'univers. Au bout de nombreuses années de travail, il avait peint un mur entier de personnages pour s'apercevoir qu'en fait il n'avait peint que son propre visage. Ce fut précisément la destinée de Péladan : l'auteur ne fit plus qu'un avec son personnage principal du Mage. Jamais son œuvre n'aura présenté une telle fusion entre imaginaire et réalité. (shrink)

John Anthony Crook, a Fellow of the British Academy, was a distinguished ancient historian with a special interest in Roman history and law. Among historians, his knowledge and understanding of Roman law was unequalled. Crook's academic career was spent for the most part in the University of Cambridge, and at St John's College. He entered the college as an undergraduate in 1939, and served as a Fellow from 1951 until his death on September 7, 2007. Within the Faculty of Classics (...) he rose to be Professor of ancient history in 1979. Crook was born in Balham, London, the only child of a bandsman in the Grenadier Guards. In his book Law and Life of Rome, he gave a brilliant demonstration of how legal sources might be made accessible and used constructively for social history. In the late 1970s, Crook joined forces with J. G. Wolf to produce an edition of the Murecine Tablets, to which they had been drawn independently. (shrink)

Others must have shared my surprise at reading the two articles on this subject in the Classical Quarterly , one by Mr. P. H. Ling, writing ‘in the light of our present knowledge,’ and one by Professor H. J. Rose. Among the Hibeh Papyri is a fragment of an anthology which hereabouts contains quotations from Tragedy and Epicharmus. It gives four verses, the last of which was rightly identified by the editors Grenfell and Hunt. Of the lemma only a (...) spot of ink on a loose fibre remains. (shrink)

Philosophers agree that scientific explanations aim to produce understanding, and that good ones succeed in this aim. But few seriously consider what understanding is, or what the cues are when we have it. If it is a psychological state or process, describing its specific nature is the job of psychological theorizing. This article examines the role of understanding in scientific explanation. It warns that the seductive, phenomenological sense of understanding is often, but mistakenly, viewed as a cue of genuine understanding. (...) The article closes with a discussion of several new paths of research that tie the psychology of scientific explanation to cognate notions of learning, testimony, and understanding. (shrink)

There is now a considerable literature on Michel Foucault but this is the first monograph which explicitly addresses his influence and impact upon education. Personal autonomy has been seen as a major aim, if not the aim of liberal education. But if Foucault is correct that personal autonomy and the notion of the autonomous person are myths, then the pursuit of such an aim by educationalists is misguided. The author develops this critique of personal autonomy and liberal education from the (...) writings of Foucault, and also considers Foucault's own educational practices. The author, James Marshall, who lives in New Zealand, has already written several articles for academic journals on Foucault. (shrink)